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Improving treatment outcome assessment in a mouse tuberculosis model

Preclinical treatment outcome evaluation of tuberculosis (TB) occurs primarily in mice. Current designs compare relapse rates of different regimens at selected time points, but lack information about the correlation between treatment length and treatment outcome, which is required to efficiently est...

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Detalles Bibliográficos
Autores principales: Mourik, Bas C., Svensson, Robin J., de Knegt, Gerjo J., Bax, Hannelore I., Verbon, Annelies, Simonsson, Ulrika S. H., de Steenwinkel, Jurriaan E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890284/
https://www.ncbi.nlm.nih.gov/pubmed/29632372
http://dx.doi.org/10.1038/s41598-018-24067-x