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Improving treatment outcome assessment in a mouse tuberculosis model
Preclinical treatment outcome evaluation of tuberculosis (TB) occurs primarily in mice. Current designs compare relapse rates of different regimens at selected time points, but lack information about the correlation between treatment length and treatment outcome, which is required to efficiently est...
Autores principales: | Mourik, Bas C., Svensson, Robin J., de Knegt, Gerjo J., Bax, Hannelore I., Verbon, Annelies, Simonsson, Ulrika S. H., de Steenwinkel, Jurriaan E. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890284/ https://www.ncbi.nlm.nih.gov/pubmed/29632372 http://dx.doi.org/10.1038/s41598-018-24067-x |
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