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Enhancing viral vaccine production using engineered knockout vero cell lines – A second look

The global adoption of vaccines to combat disease is hampered by the high cost of vaccine manufacturing. The work described herein follows two previous publications (van der Sanden et al., 2016; Wu et al., 2017) that report a strategy to enhance poliovirus and rotavirus vaccine production through ge...

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Detalles Bibliográficos
Autores principales: Hoeksema, F., Karpilow, J., Luitjens, A., Lagerwerf, F., Havenga, M., Groothuizen, M., Gillissen, G., Lemckert, A.A.C., Jiang, B., Tripp, R.A., Yallop, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890396/
https://www.ncbi.nlm.nih.gov/pubmed/29555218
http://dx.doi.org/10.1016/j.vaccine.2018.03.010