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Uromodulin rs4293393 T>C variation is associated with kidney disease in patients with type 2 diabetes
BACKGROUND & OBJECTIVES: Uromodulin, a UMOD gene encoded glycoprotein is synthesized exclusively in renal tubular cells and released into urine. Mutations lead to uromodulin misfolding and retention in the kidney, where it might stimulate cells of immune system to cause inflammation and progress...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890591/ https://www.ncbi.nlm.nih.gov/pubmed/29578190 http://dx.doi.org/10.4103/ijmr.IJMR_919_16 |