Changes in macrophage transcriptome associate with systemic sclerosis and mediate GSDMA contribution to disease risk

OBJECTIVES: Several common and rare risk variants have been reported for systemic sclerosis (SSc), but the effector cell(s) mediating the function of these genetic variants remains to be elucidated. While innate immune cells have been proposed as the critical targets to interfere with the disease pr...

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Detalles Bibliográficos
Autores principales: Moreno-Moral, Aida, Bagnati, Marta, Koturan, Surya, Ko, Jeong-Hun, Fonseca, Carmen, Harmston, Nathan, Game, Laurence, Martin, Javier, Ong, Voon, Abraham, David J, Denton, Christopher P, Behmoaras, Jacques, Petretto, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Basic and Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890626/
https://www.ncbi.nlm.nih.gov/pubmed/29348297
http://dx.doi.org/10.1136/annrheumdis-2017-212454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890626/
https://www.ncbi.nlm.nih.gov/pubmed/29348297
http://dx.doi.org/10.1136/annrheumdis-2017-212454

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