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Clinical implications of Plasmodium resistance to atovaquone/proguanil: a systematic review and meta-analysis

BACKGROUND: Atovaquone/proguanil, registered as Malarone(®), is a fixed-dose combination recommended for first-line treatment of uncomplicated Plasmodium falciparum malaria in non-endemic countries and its prevention in travellers. Mutations in the cytochrome bc(1) complex are causally associated wi...

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Detalles Bibliográficos
Autores principales: Staines, Henry M, Burrow, Rebekah, Teo, Beatrix Huei-Yi, Chis Ster, Irina, Kremsner, Peter G, Krishna, Sanjeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890752/
https://www.ncbi.nlm.nih.gov/pubmed/29237012
http://dx.doi.org/10.1093/jac/dkx431