Modelling of mycobacterial load reveals bedaquiline’s exposure–response relationship in patients with drug-resistant TB

BACKGROUND: Bedaquiline has been shown to reduce time to sputum culture conversion (SCC) and increase cure rates in patients with drug-resistant TB, but the influence of drug exposure remains uncharacterized. OBJECTIVES: To investigate whether an exposure–response relationship could be characterized...

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Detalles Bibliográficos
Autores principales: Svensson, Elin M, Karlsson, Mats O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890768/
https://www.ncbi.nlm.nih.gov/pubmed/28961790
http://dx.doi.org/10.1093/jac/dkx317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890768/
https://www.ncbi.nlm.nih.gov/pubmed/28961790
http://dx.doi.org/10.1093/jac/dkx317

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