Total chemical synthesis of glycocin F and analogues: S-glycosylation confers improved antimicrobial activity

Glycocin F (GccF) is a unique diglycosylated bacteriocin peptide that possesses potent and reversible bacteriostatic activity against a range of Gram-positive bacteria. GccF is a rare example of a ‘glycoactive’ bacteriocin, with both the O-linked N-acetylglucosamine (GlcNAc) and the unusual S-linked...

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Detalles Bibliográficos
Autores principales: Amso, Zaid, Bisset, Sean W., Yang, Sung-Hyun, Harris, Paul W. R., Wright, Tom H., Navo, Claudio D., Patchett, Mark L., Norris, Gillian E., Brimble, Margaret A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890784/
https://www.ncbi.nlm.nih.gov/pubmed/29675216
http://dx.doi.org/10.1039/c7sc04383j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890784/
https://www.ncbi.nlm.nih.gov/pubmed/29675216
http://dx.doi.org/10.1039/c7sc04383j

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