Cargando…

Total chemical synthesis of glycocin F and analogues: S-glycosylation confers improved antimicrobial activity

Glycocin F (GccF) is a unique diglycosylated bacteriocin peptide that possesses potent and reversible bacteriostatic activity against a range of Gram-positive bacteria. GccF is a rare example of a ‘glycoactive’ bacteriocin, with both the O-linked N-acetylglucosamine (GlcNAc) and the unusual S-linked...

Descripción completa

Detalles Bibliográficos
Autores principales:	Amso, Zaid, Bisset, Sean W., Yang, Sung-Hyun, Harris, Paul W. R., Wright, Tom H., Navo, Claudio D., Patchett, Mark L., Norris, Gillian E., Brimble, Margaret A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2018
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890784/ https://www.ncbi.nlm.nih.gov/pubmed/29675216 http://dx.doi.org/10.1039/c7sc04383j

Ejemplares similares

Heterologous biosynthesis and characterization of a glycocin from a thermophilic bacterium
por: Kaunietis, Arnoldas, et al.
Publicado: (2019)

Differential expression of a prophage-encoded glycocin and its immunity protein suggests a mutualistic strategy of a phage and its host
por: Denham, Emma L., et al.
Publicado: (2019)

A synthetic approach to ‘click’ neoglycoprotein analogues of EPO employing one-pot native chemical ligation and CuAAC chemistry
por: Lee, D. J., et al.
Publicado: (2018)

Synthesis and activity of a diselenide bond mimetic of the antimicrobial protein caenopore-5
por: Medini, Karima, et al.
Publicado: (2016)

Synthesis and Systematic Study on the Effect of Different PEG Units on Stability of PEGylated, Integrin-αvβ6-Specific A20FMDV2 Analogues in Rat Serum and Human Plasma
por: Hung, Kuo-yuan, et al.
Publicado: (2022)

Synthesis of Fluorescent Lanthipeptide Cytolysin S Analogues by Late-Stage Sulfamidate Ring Opening
por: Mazo, Nuria, et al.
Publicado: (2023)

Flow-Based Fmoc-SPPS Preparation and SAR Study of Cathelicidin-PY Reveals Selective Antimicrobial Activity
por: Dissanayake, Shama, et al.
Publicado: (2023)

Impact of Acetylated and Non-Acetylated Fucose Analogues on IgG Glycosylation
por: Zimmermann, Martina, et al.
Publicado: (2019)

A Concise Synthetic Strategy Towards the Novel Calcium-dependent Lipopeptide Antibiotic, Malacidin A and Analogues
por: Kovalenko, Nadiia, et al.
Publicado: (2021)

Antimicrobial Evaluation of Mangiferin Analogues
por: Singh, S. K., et al.
Publicado: (2009)

Antimicrobial Activity of Resveratrol Analogues
por: Chalal, Malik, et al.
Publicado: (2014)

LARGE2-dependent glycosylation confers laminin-binding ability on proteoglycans
por: Inamori, Kei-ichiro, et al.
Publicado: (2016)

Synthesis of glycosylated β(3)-homo-threonine conjugates for mucin-like glycopeptide antigen analogues
por: Karch, Florian, et al.
Publicado: (2010)

Glycosylated Lipopeptides—Synthesis and Evaluation of Antimicrobial Activity and Cytotoxicity
por: Sikora, Karol, et al.
Publicado: (2023)

Increased Biomass, Seed Yield and Stress Tolerance Is Conferred in Arabidopsis by a Novel Enzyme from the Resurrection Grass Sporobolus stapfianus That Glycosylates the Strigolactone Analogue GR24
por: Islam, Sharmin, et al.
Publicado: (2013)

Antimicrobial activity of indole-based melatonin analogues
por: Shirinzadeh, H, et al.
Publicado: (2012)

An Insight into FDA Approved Antibody-Drug Conjugates for Cancer Therapy
por: Tong, Juliana T. W., et al.
Publicado: (2021)

Combining triazole ligation and enzymatic glycosylation on solid phase simplifies the synthesis of very long glycoprotein analogues
por: Galibert, Mathieu, et al.
Publicado: (2015)

The impact of N-glycosylation on the properties of the antimicrobial peptide LL-III
por: Tortorella, Attila, et al.
Publicado: (2023)

Glycosylation and Lipidation Strategies: Approaches for Improving Antimicrobial Peptide Efficacy
por: Bellavita, Rosa, et al.
Publicado: (2023)

Three Decades of Amyloid Beta Synthesis: Challenges and Advances
por: Kasim, Johanes K., et al.
Publicado: (2019)

Aminovinyl Cysteine Containing Peptides: A Unique Motif That Imparts Key Biological Activity
por: Grant-Mackie, Emily S., et al.
Publicado: (2021)

Anti-inflammatory and antimicrobial activities of novel pyrazole analogues
por: Surendra Kumar, R., et al.
Publicado: (2016)

Antimicrobial Activity of Xanthohumol and Its Selected Structural Analogues
por: Stompor, Monika, et al.
Publicado: (2016)

Synthesis and Antimicrobial Activity of δ-Viniferin Analogues and Isosteres
por: Mattio, Luce Micaela, et al.
Publicado: (2021)

First-in-Class Cyclic Temporin L Analogue: Design, Synthesis, and Antimicrobial Assessment
por: Bellavita, Rosa, et al.
Publicado: (2021)

Modulable Photocatalyzed Strategies for the Synthesis of α-C-Glycosyl Alanine Analogues via the Giese Reaction with Dehydroalanine Derivates
por: Poletti, Lorenzo, et al.
Publicado: (2023)

Silver-promoted solid-phase guanidinylation enables the first synthesis of arginine glycosylated Samoamide A cyclopeptide analogue
por: Liang, Bingxin, et al.
Publicado: (2023)

Mucin 21 confers resistance to apoptosis in an O-glycosylation-dependent manner
por: Tian, Yuan, et al.
Publicado: (2022)

Antimicrobial Activity of the Marine Alkaloids, Clathrodin and Oroidin, and Their Synthetic Analogues
por: Zidar, Nace, et al.
Publicado: (2014)

Synthesis of cyclotetrapeptide analogues of c-PLAI and evaluation of their antimicrobial properties
por: Maharani, Rani, et al.
Publicado: (2021)

Anticoronavirus Evaluation of Antimicrobial Diterpenoids: Application of New Ferruginol Analogues
por: Varbanov, Mihayl, et al.
Publicado: (2023)

Solid‐Phase Synthesis of Fluorinated Analogues of Glycosyl 1‐Phosphate Repeating Structures from Leishmania using the Phosphoramidite Method
por: Hara, Rintaro Iwata, et al.
Publicado: (2018)

Characterization of Posttranslationally Modified Multidrug Efflux Pumps Reveals an Unexpected Link between Glycosylation and Antimicrobial Resistance
por: Abouelhadid, Sherif, et al.
Publicado: (2020)

Structure and Activity of Streptococcus pyogenes SipA: A Signal Peptidase-Like Protein Essential for Pilus Polymerisation
por: Young, Paul G., et al.
Publicado: (2014)

Identification of Key Functional Motifs of Native Amelogenin Protein for Dental Enamel Remineralisation
por: Dissanayake, Shama S. M., et al.
Publicado: (2020)

Thiol-ene Enabled Chemical Synthesis of Truncated S-Lipidated Teixobactin Analogs
por: Yim, Victor V., et al.
Publicado: (2020)

Peptide Lipidation – A Synthetic Strategy to Afford Peptide Based Therapeutics
por: Kowalczyk, Renata, et al.
Publicado: (2017)

Glycosylation's active site—finally
por: Dove, Alan W.
Publicado: (2003)

Novel α-MSH Peptide Analogues with Broad Spectrum Antimicrobial Activity
por: Grieco, Paolo, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_1qavohv7tvo8f7favl59sv92j4