Rhodium-catalyzed asymmetric hydrogenation of β-cyanocinnamic esters with the assistance of a single hydrogen bond in a precise position

With the assistance of hydrogen bonds, the first asymmetric hydrogenation of β-cyanocinnamic esters is developed, affording chiral β-cyano esters with excellent enantioselectivities (up to 99% ee). This novel methodology provides an efficient and concise synthetic route to chiral GABA-derivatives su...

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Detalles Bibliográficos
Autores principales: Li, Xiuxiu, You, Cai, Yang, Yusheng, Yang, Yuhong, Li, Pan, Gu, Guoxian, Chung, Lung Wa, Lv, Hui, Zhang, Xumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890790/
https://www.ncbi.nlm.nih.gov/pubmed/29675238
http://dx.doi.org/10.1039/c7sc04639a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890790/
https://www.ncbi.nlm.nih.gov/pubmed/29675238
http://dx.doi.org/10.1039/c7sc04639a

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