Cargando…

Midlife stress alters memory and mood-related behaviors in old age: Role of locally activated glucocorticoids

Chronic exposure to stress during midlife associates with subsequent age-related cognitive decline and may increase the vulnerability to develop psychiatric conditions. Increased hypothalamic-pituitary-adrenal (HPA) axis activity has been implicated in pathogenesis though any causative role for gluc...

Descripción completa

Detalles Bibliográficos
Autores principales: Wheelan, Nicola, Kenyon, Christopher J., Harris, Anjanette P., Cairns, Carolynn, Al Dujaili, Emad, Seckl, Jonathan R., Yau, Joyce L.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890827/
https://www.ncbi.nlm.nih.gov/pubmed/29306773
http://dx.doi.org/10.1016/j.psyneuen.2017.12.018