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Midlife stress alters memory and mood-related behaviors in old age: Role of locally activated glucocorticoids
Chronic exposure to stress during midlife associates with subsequent age-related cognitive decline and may increase the vulnerability to develop psychiatric conditions. Increased hypothalamic-pituitary-adrenal (HPA) axis activity has been implicated in pathogenesis though any causative role for gluc...
Autores principales: | Wheelan, Nicola, Kenyon, Christopher J., Harris, Anjanette P., Cairns, Carolynn, Al Dujaili, Emad, Seckl, Jonathan R., Yau, Joyce L.W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pergamon Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890827/ https://www.ncbi.nlm.nih.gov/pubmed/29306773 http://dx.doi.org/10.1016/j.psyneuen.2017.12.018 |
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