Autoimmunity associated with chemically induced thymic dysplasia

Autoimmune and inflammatory conditions are frequent complications in patients with reduced numbers of T cells. Here, we describe a mouse model of thymic stromal dysplasia resulting in peripheral T-cell lymphopenia. In Foxn1:CFP-NTR transgenic mice, the bacterial nitroreductase enzyme is expressed in...

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Detalles Bibliográficos
Autores principales: Nagakubo, Daisuke, Swann, Jeremy B, Birmelin, Stefanie, Boehm, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890891/
https://www.ncbi.nlm.nih.gov/pubmed/28992076
http://dx.doi.org/10.1093/intimm/dxx048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890891/
https://www.ncbi.nlm.nih.gov/pubmed/28992076
http://dx.doi.org/10.1093/intimm/dxx048

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