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Autoimmunity associated with chemically induced thymic dysplasia

Autoimmune and inflammatory conditions are frequent complications in patients with reduced numbers of T cells. Here, we describe a mouse model of thymic stromal dysplasia resulting in peripheral T-cell lymphopenia. In Foxn1:CFP-NTR transgenic mice, the bacterial nitroreductase enzyme is expressed in...

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Detalles Bibliográficos
Autores principales:	Nagakubo, Daisuke, Swann, Jeremy B, Birmelin, Stefanie, Boehm, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Short Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890891/ https://www.ncbi.nlm.nih.gov/pubmed/28992076 http://dx.doi.org/10.1093/intimm/dxx048

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