ERASE-Seq: Leveraging replicate measurements to enhance ultralow frequency variant detection in NGS data

The accurate detection of ultralow allele frequency variants in DNA samples is of interest in both research and medical settings, particularly in liquid biopsies where cancer mutational status is monitored from circulating DNA. Next-generation sequencing (NGS) technologies employing molecular barcod...

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Detalles Bibliográficos
Autores principales: Kamps-Hughes, Nick, McUsic, Andrew, Kurihara, Laurie, Harkins, Timothy T., Pal, Prithwish, Ray, Claire, Ionescu-Zanetti, Cristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890993/
https://www.ncbi.nlm.nih.gov/pubmed/29630678
http://dx.doi.org/10.1371/journal.pone.0195272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890993/
https://www.ncbi.nlm.nih.gov/pubmed/29630678
http://dx.doi.org/10.1371/journal.pone.0195272

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