Cargando…
ERASE-Seq: Leveraging replicate measurements to enhance ultralow frequency variant detection in NGS data
The accurate detection of ultralow allele frequency variants in DNA samples is of interest in both research and medical settings, particularly in liquid biopsies where cancer mutational status is monitored from circulating DNA. Next-generation sequencing (NGS) technologies employing molecular barcod...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890993/ https://www.ncbi.nlm.nih.gov/pubmed/29630678 http://dx.doi.org/10.1371/journal.pone.0195272 |