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The use of plant lectins to regulate H1N1 influenza A virus receptor binding activity

We applied an in vitro selection approach using two different plant lectins that bind to α2,3- or α2,6-linked sialic acids to determine which genetic changes of the A/California/04/09 (H1N1) virus alter hemagglutinin (HA) receptor binding toward α2,3- or α2,6-linked glycans. Consecutive passages of...

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Detalles Bibliográficos
Autores principales: Lee, Nicolette, Khalenkov, Alexey M., Lugovtsev, Vladimir Y., Ireland, Derek D., Samsonova, Anastasia P., Bovin, Nicolai V., Donnelly, Raymond P., Ilyushina, Natalia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891020/
https://www.ncbi.nlm.nih.gov/pubmed/29630683
http://dx.doi.org/10.1371/journal.pone.0195525