Activation of TNF‐α/NF‐κB axis enhances CRL4B(DCAF) (11) E3 ligase activity and regulates cell cycle progression in human osteosarcoma cells

Cullin 4B, a member of the Cullins, which serve as scaffolds to facilitate the assembly of E3 ligase complexes, is aberrantly expressed in many cancers, including osteosarcoma. Recently, we observed that CUL4B forms the CRL4B(DCAF) (11) E3 ligase, which specifically ubiquitinates and degrades the cy...

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Detalles Bibliográficos
Autores principales: Zhang, Caiguo, Chen, Bin, Jiang, Kaibiao, Lao, Lifeng, Shen, Hongxing, Chen, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891038/
https://www.ncbi.nlm.nih.gov/pubmed/29377600
http://dx.doi.org/10.1002/1878-0261.12176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891038/
https://www.ncbi.nlm.nih.gov/pubmed/29377600
http://dx.doi.org/10.1002/1878-0261.12176

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