CQ sensitizes human pancreatic cancer cells to gemcitabine through the lysosomal apoptotic pathway via reactive oxygen species

As an established anticancer drug, gemcitabine (GEM) is an effective systemic treatment for advanced pancreatic cancer (PC). However, little is known about the potential effectors that may modify tumour cell sensitivity towards GEM. Autophagy, as a physiological cellular mechanism, is involved in bo...

Descripción completa

Detalles Bibliográficos
Autores principales: Fu, Zhiping, Cheng, Xi, Kuang, Jie, Feng, Haoran, Chen, Lingxie, Liang, Juyong, Shen, Xiaonan, Yuen, Stanley, Peng, Chenghong, Shen, Baiyong, Jin, Zhijian, Qiu, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891043/
https://www.ncbi.nlm.nih.gov/pubmed/29453806
http://dx.doi.org/10.1002/1878-0261.12179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891043/
https://www.ncbi.nlm.nih.gov/pubmed/29453806
http://dx.doi.org/10.1002/1878-0261.12179

Ejemplares similares