Electrophysiological mechanisms of vandetanib-induced cardiotoxicity: Comparison of action potentials in rabbit Purkinje fibers and pluripotent stem cell-derived cardiomyocytes

Vandetanib, a multi-kinase inhibitor used for the treatment of various cancers, has been reported to induce several adverse cardiac effects. However, the underlying mechanisms of vandetanib-induced cardiotoxicity are unclear. This study aimed to investigate the mechanism of vandetanib-induced cardio...

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Detalles Bibliográficos
Autores principales: Lee, Hyang-Ae, Hyun, Sung-Ae, Byun, Byungjin, Chae, Jong-Hak, Kim, Ki-Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891061/
https://www.ncbi.nlm.nih.gov/pubmed/29630634
http://dx.doi.org/10.1371/journal.pone.0195577

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891061/
https://www.ncbi.nlm.nih.gov/pubmed/29630634
http://dx.doi.org/10.1371/journal.pone.0195577

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