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Large scale variation in the rate of germ-line de novo mutation, base composition, divergence and diversity in humans
It has long been suspected that the rate of mutation varies across the human genome at a large scale based on the divergence between humans and other species. However, it is now possible to directly investigate this question using the large number of de novo mutations (DNMs) that have been discovere...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891062/ https://www.ncbi.nlm.nih.gov/pubmed/29590096 http://dx.doi.org/10.1371/journal.pgen.1007254 |