Astrocytic Kir4.1 channels and gap junctions account for spontaneous epileptic seizure

Experimental recordings in hippocampal slices indicate that astrocytic dysfunction may cause neuronal hyper-excitation or seizures. Considering that astrocytes play important roles in mediating local uptake and spatial buffering of K(+) in the extracellular space of the cortical circuit, we construc...

Descripción completa

Detalles Bibliográficos
Autores principales: Du, Mengmeng, Li, Jiajia, Chen, Liang, Yu, Yuguo, Wu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891073/
https://www.ncbi.nlm.nih.gov/pubmed/29590095
http://dx.doi.org/10.1371/journal.pcbi.1005877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891073/
https://www.ncbi.nlm.nih.gov/pubmed/29590095
http://dx.doi.org/10.1371/journal.pcbi.1005877

Ejemplares similares