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Astrocytic Kir4.1 channels and gap junctions account for spontaneous epileptic seizure
Experimental recordings in hippocampal slices indicate that astrocytic dysfunction may cause neuronal hyper-excitation or seizures. Considering that astrocytes play important roles in mediating local uptake and spatial buffering of K(+) in the extracellular space of the cortical circuit, we construc...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891073/ https://www.ncbi.nlm.nih.gov/pubmed/29590095 http://dx.doi.org/10.1371/journal.pcbi.1005877 |