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Tunicamycin inhibits cell proliferation and migration in hepatocellular carcinoma through suppression of CD44s and the ERK1/2 pathway

Tunicamycin (TM) is an N‐linked glycosylation (NLG) inhibitor with strong antitumor activity, the exact underlying molecular mechanism of which remains to be elucidated. In our previous studies, we found that TM reversed drug resistance and improved the efficacy of combination treatments for hepatoc...

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Detalles Bibliográficos
Autores principales: Hou, Helei, Ge, Chao, Sun, Hefen, Li, Hong, Li, Jinjun, Tian, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891198/
https://www.ncbi.nlm.nih.gov/pubmed/29377347
http://dx.doi.org/10.1111/cas.13518