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FBW7 is associated with prognosis, inhibits malignancies and enhances temozolomide sensitivity in glioblastoma cells

F‐box and WD repeat domain‐containing 7 (FBW7) is a SCF‐type E3 ubiquitin ligase targeting a multitude of oncoproteins for degradation. Acting as one of the most important tumor suppressors, it is frequently inactivated in various tumors. In this study we aimed to evaluate the relationship of FBW7 w...

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Detalles Bibliográficos
Autores principales: Lin, Jing, Ji, Aihui, Qiu, Guanzhong, Feng, Huaizhi, Li, Jian, Li, Shuo, Zou, Yongxiang, Cui, Yong, Song, Chaoli, He, Hua, Lu, Yicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891203/
https://www.ncbi.nlm.nih.gov/pubmed/29427543
http://dx.doi.org/10.1111/cas.13528