PAWS1 controls Wnt signalling through association with casein kinase 1α

The BMP and Wnt signalling pathways determine axis specification during embryonic development. Our previous work has shown that PAWS1 (also known as FAM83G) interacts with SMAD1 and modulates BMP signalling. Here, surprisingly, we show that overexpression of PAWS1 in Xenopus embryos activates Wnt si...

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Detalles Bibliográficos
Autores principales: Bozatzi, Polyxeni, Dingwell, Kevin S, Wu, Kevin ZL, Cooper, Fay, Cummins, Timothy D, Hutchinson, Luke D, Vogt, Janis, Wood, Nicola T, Macartney, Thomas J, Varghese, Joby, Gourlay, Robert, Campbell, David G, Smith, James C, Sapkota, Gopal P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891436/
https://www.ncbi.nlm.nih.gov/pubmed/29514862
http://dx.doi.org/10.15252/embr.201744807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891436/
https://www.ncbi.nlm.nih.gov/pubmed/29514862
http://dx.doi.org/10.15252/embr.201744807

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