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PAWS1 controls Wnt signalling through association with casein kinase 1α
The BMP and Wnt signalling pathways determine axis specification during embryonic development. Our previous work has shown that PAWS1 (also known as FAM83G) interacts with SMAD1 and modulates BMP signalling. Here, surprisingly, we show that overexpression of PAWS1 in Xenopus embryos activates Wnt si...
Autores principales: | Bozatzi, Polyxeni, Dingwell, Kevin S, Wu, Kevin ZL, Cooper, Fay, Cummins, Timothy D, Hutchinson, Luke D, Vogt, Janis, Wood, Nicola T, Macartney, Thomas J, Varghese, Joby, Gourlay, Robert, Campbell, David G, Smith, James C, Sapkota, Gopal P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891436/ https://www.ncbi.nlm.nih.gov/pubmed/29514862 http://dx.doi.org/10.15252/embr.201744807 |
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