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KRDS: a web server for evaluating drug resistance mutations in kinases by molecular docking
Kinases are major targets of anti-cancer therapies owing to their importance in signaling processes that regulate cell growth and proliferation. However, drug resistance has emerged as a major obstacle to cancer therapy. Resistance to drugs has various underlying mechanisms, including the acquisitio...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891443/ https://www.ncbi.nlm.nih.gov/pubmed/29633047 http://dx.doi.org/10.1186/s13321-018-0274-y |