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Can a Proper T-Cell Development Occur in an Altered Thymic Epithelium? Lessons From EphB-Deficient Thymi

For a long time, the effects of distinct Eph tyrosine kinase receptors and their ligands, ephrins on the structure, immunophenotype, and development of thymus and their main cell components, thymocytes (T) and thymic epithelial cells (TECs), have been studied. In recent years, the thymic phenotype o...

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Detalles Bibliográficos
Autores principales: Muñoz, Juan José, García-Ceca, Javier, Montero-Herradón, Sara, Sánchez del Collado, Beatriz, Alfaro, David, Zapata, Agustín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891583/
https://www.ncbi.nlm.nih.gov/pubmed/29666605
http://dx.doi.org/10.3389/fendo.2018.00135