Reassortant H5N1 Avian Influenza Virus Bearing PB2 Gene From a 2009 Pandemic H1N1 Exhibits Increased Pathogenicity in Mice

Reassortment is a key driving force of the evolution and host adaptation of the influenza virus. A(H1N1)pdm2009 (pdm09), a novel H1N1 influenza viral subtype, caused a pandemic in 2009. The strain was established in pig herds and cocirculated with the highly pathogenic H5N1 avian influenza virus. Th...

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Detalles Bibliográficos
Autores principales: Lin, Xian, Yu, Shiman, Guo, Kelei, Sun, Xin, Yi, Haiming, Jin, Meilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891601/
https://www.ncbi.nlm.nih.gov/pubmed/29666618
http://dx.doi.org/10.3389/fmicb.2018.00631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891601/
https://www.ncbi.nlm.nih.gov/pubmed/29666618
http://dx.doi.org/10.3389/fmicb.2018.00631

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