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PLCζ Induced Ca(2+) Oscillations in Mouse Eggs Involve a Positive Feedback Cycle of Ca(2+) Induced InsP(3) Formation From Cytoplasmic PIP(2)

Egg activation at fertilization in mammalian eggs is caused by a series of transient increases in the cytosolic free Ca(2+) concentration, referred to as Ca(2+) oscillations. It is widely accepted that these Ca(2+) oscillations are initiated by a sperm derived phospholipase C isoform, PLCζ that hydr...

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Detalles Bibliográficos
Autores principales: Sanders, Jessica R., Ashley, Bethany, Moon, Anna, Woolley, Thomas E., Swann, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891639/
https://www.ncbi.nlm.nih.gov/pubmed/29666796
http://dx.doi.org/10.3389/fcell.2018.00036