Optimized Phenotypic Biomarker Discovery and Confounder Elimination via Covariate-Adjusted Projection to Latent Structures from Metabolic Spectroscopy Data

[Image: see text] Metabolism is altered by genetics, diet, disease status, environment, and many other factors. Modeling either one of these is often done without considering the effects of the other covariates. Attributing differences in metabolic profile to one of these factors needs to be done wh...

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Detalles Bibliográficos
Autores principales: Posma, Joram M., Garcia-Perez, Isabel, Ebbels, Timothy M. D., Lindon, John C., Stamler, Jeremiah, Elliott, Paul, Holmes, Elaine, Nicholson, Jeremy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891819/
https://www.ncbi.nlm.nih.gov/pubmed/29457906
http://dx.doi.org/10.1021/acs.jproteome.7b00879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891819/
https://www.ncbi.nlm.nih.gov/pubmed/29457906
http://dx.doi.org/10.1021/acs.jproteome.7b00879

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