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Withania somnifera modulates cancer cachexia associated inflammatory cytokines and cell death in leukaemic THP-1 cells and peripheral blood mononuclear cells (PBMC’s)

BACKGROUND: Cancer and inflammation are associated with cachexia. Withania somnifera (W. somnifera) possesses antioxidant and anti-inflammatory potential. We investigated the potential of an aqueous extract of the root of W. somnifera (W(RE)) to modulate cytokines, antioxidants and apoptosis in leuk...

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Detalles Bibliográficos
Autores principales: Naidoo, Dhaneshree Bestinee, Chuturgoon, Anil Amichund, Phulukdaree, Alisa, Guruprasad, Kanive Parashiva, Satyamoorthy, Kapaettu, Sewram, Vikash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891897/
https://www.ncbi.nlm.nih.gov/pubmed/29631586
http://dx.doi.org/10.1186/s12906-018-2192-y