Histone hypo-acetylation of Sox9 mediates nicotine-induced weak cartilage repair by suppressing BMSC chondrogenic differentiation

BACKGROUND: Nicotine has negative effects on tissue repair, little research concerns its effect on the cartilage repair of tissue engineering stem cells. The present study aimed to investigate the effects of nicotine on the bone marrow-derived mesenchymal stem cells’ (BMSCs) chondrogenic repair func...

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Detalles Bibliográficos
Autores principales: Tie, Kai, Wu, Min, Deng, Yu, Wen, Yinxian, Dan Xu, Chen, Liaobin, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891899/
https://www.ncbi.nlm.nih.gov/pubmed/29631619
http://dx.doi.org/10.1186/s13287-018-0853-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891899/
https://www.ncbi.nlm.nih.gov/pubmed/29631619
http://dx.doi.org/10.1186/s13287-018-0853-x

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