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Crocin attenuates cigarette smoke-induced lung injury and cardiac dysfunction by anti-oxidative effects: the role of Nrf2 antioxidant system in preventing oxidative stress

BACKGROUND: Chronic obstructive pulmonary disease (COPD) has been emerging as a great health problem in world. Cigarette smoke is known to cause oxidative stress and deplete glutathione (GSH) levels. Nuclear erythroid-related factor 2 (Nrf2) is involved in transcriptional regulation of glutamate-cys...

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Detalles Bibliográficos
Autores principales: Dianat, Mahin, Radan, Maryam, Badavi, Mohammad, Mard, Seyyed Ali, Bayati, Vahid, Ahmadizadeh, Masoumeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891913/
https://www.ncbi.nlm.nih.gov/pubmed/29631592
http://dx.doi.org/10.1186/s12931-018-0766-3