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Neurofilament light as a blood biomarker for neurodegeneration in Down syndrome
BACKGROUND: Down syndrome (DS) may be considered a genetic form of Alzheimer’s disease (AD) due to universal development of AD neuropathology, but diagnosis and treatment trials are hampered by a lack of reliable blood biomarkers. A potential biomarker is neurofilament light (NF-L), due to its assoc...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891918/ https://www.ncbi.nlm.nih.gov/pubmed/29631614 http://dx.doi.org/10.1186/s13195-018-0367-x |