MDR1 overexpression combined with ERG11 mutations induce high-level fluconazole resistance in Candida tropicalis clinical isolates

BACKGROUND: Marked increases in fluconazole resistance in Candida tropicalis have been recently reported. In this study, the molecular mechanisms behind fluconazole resistance were investigated. METHODS: Twenty-two C. tropicalis clinical isolates, including 12 fluconazole-resistant isolates and 10 f...

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Detalles Bibliográficos
Autores principales: Jin, Longyang, Cao, Zhuorui, Wang, Qi, Wang, Yichen, Wang, Xiaojuan, Chen, Hongbin, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891969/
https://www.ncbi.nlm.nih.gov/pubmed/29631565
http://dx.doi.org/10.1186/s12879-018-3082-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891969/
https://www.ncbi.nlm.nih.gov/pubmed/29631565
http://dx.doi.org/10.1186/s12879-018-3082-0

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