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Alternative splicing of human telomerase reverse transcriptase in gliomas and its modulation mediated by CX-5461
BACKGROUND: Glioma is a heterogeneous, invasive primary brain tumor with a wide range of patient survival and a lack of reliable prognostic biomarkers. Human telomerase reverse transcriptase (hTERT) has been reported in the presence of multiple transcripts in various tumor systems. The biological fu...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891986/ https://www.ncbi.nlm.nih.gov/pubmed/29631594 http://dx.doi.org/10.1186/s13046-018-0749-8 |