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Iatrogenic metrorrhagia after the use of itraconazole for onychomycosis

We present first case report on itraconazole, a drug very commonly used for onychomycosis, used along with simvastatin that caused metrorrhagia. The suggested probable mechanism is the inhibition of steroidogenesis, especially estrogens that resulted in low-estrogen breakthrough bleeding. This artic...

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Detalles Bibliográficos
Autores principales: Brzezinski, Piotr, Gulin, Sandra Jerkovic, Gulin, Dario, Chiriac, Anca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892030/
https://www.ncbi.nlm.nih.gov/pubmed/29674803
http://dx.doi.org/10.4103/ijp.IJP_838_16