GAD65 autoantibody characteristics in patients with co-occurring type 1 diabetes and epilepsy may help identify underlying epilepsy etiologies

BACKGROUND: Autoantibodies against the smaller isoform of glutamate decarboxylase (GAD65Ab) reflect autoimmune etiologies in Type 1 diabetes (T1D) and several neurological disorders, including Stiff Person Syndrome (SPS). GAD65Ab are also reported in cases of epilepsy, indicating an autoimmune compo...

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Detalles Bibliográficos
Autores principales: Liimatainen, Suvi, Honnorat, Jerome, Pittock, Sean J., McKeon, Andrew, Manto, Mario, Radtke, Jared R., Hampe, Christiane S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892043/
https://www.ncbi.nlm.nih.gov/pubmed/29636076
http://dx.doi.org/10.1186/s13023-018-0787-5