Single blood transfusion induces the production of donor-specific alloantibodies and regulatory T cells mainly in the spleen

Donor-specific blood transfusion is known to induce alloresponses and lead to immunosuppression. We examined their underlying mechanisms by employing fully allogeneic rat combinations. Transfused recipients efficiently produced alloantibodies of the IgM and IgG subclasses directed against donor clas...

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Detalles Bibliográficos
Autores principales: Ueta, Hisashi, Kitazawa, Yusuke, Sawanobori, Yasushi, Ueno, Takamasa, Ueha, Satoshi, Matsushima, Kouji, Matsuno, Kenjiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Original Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892146/
https://www.ncbi.nlm.nih.gov/pubmed/29361165
http://dx.doi.org/10.1093/intimm/dxx078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892146/
https://www.ncbi.nlm.nih.gov/pubmed/29361165
http://dx.doi.org/10.1093/intimm/dxx078

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