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A Novel Association of Polymorphism in the ITGA4 Gene Encoding the VLA-4 α4 Subunit with Increased Risk of Alzheimer's Disease

Alzheimer's disease (AD) is the most prevalent cause of dementia in elderly people worldwide. Many studies support the hypothesis that the inflammation of the CNS contributes to the neurodegeneration and disease progression. The integrin molecule α4β1, also known as very late antigen 4 (VLA-4),...

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Detalles Bibliográficos
Autores principales: Durmanova, Vladimira, Parnicka, Zuzana, Javor, Juraj, Minarik, Gabriel, Vrazda, Lubomir, Vaseckova, Barbora, Gmitterova, Karin, Kralova, Maria, Pecenak, Jan, Filipcik, Peter, Shawkatova, Ivana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892238/
https://www.ncbi.nlm.nih.gov/pubmed/29769839
http://dx.doi.org/10.1155/2018/7623823