Silibinin Induced Human Glioblastoma Cell Apoptosis Concomitant with Autophagy through Simultaneous Inhibition of mTOR and YAP

Silibinin, also known as silybin, is the major flavonolignan isolated from Silybum marianum. Although previous reports demonstrated that silibinin exhibits significant tumor suppressor activities in various cancers by promoting cell apoptosis, it was also shown to trigger autophagy to counteract apo...

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Detalles Bibliográficos
Autores principales: Bai, Zhuan-Li, Tay, Vincent, Guo, Shu-Zhong, Ren, Juan, Shu, Mao-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892302/
https://www.ncbi.nlm.nih.gov/pubmed/29780826
http://dx.doi.org/10.1155/2018/6165192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892302/
https://www.ncbi.nlm.nih.gov/pubmed/29780826
http://dx.doi.org/10.1155/2018/6165192

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