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Phosphine-catalyzed [5+1] annulation of δ-sulfonamido-substituted enones with N-sulfonylimines: a facile synthesis of tetrahydropyridines

Phosphine-catalyzed [5+1] annulation of δ-sulfonamido-substituted enones with N-sulfonylimines for the synthesis of 1,2,3,6-tetrahydropyridines is developed. The reaction proceeds smoothly under mild reaction conditions to give the annulation products in moderate to excellent yields. Mechanistic exp...

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Detalles Bibliográficos
Autores principales: Zhou, Leijie, Yuan, Chunhao, Zeng, Yuan, Liu, Honglei, Wang, Chang, Gao, Xing, Wang, Qijun, Zhang, Cheng, Guo, Hongchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892350/
https://www.ncbi.nlm.nih.gov/pubmed/29675228
http://dx.doi.org/10.1039/c7sc04515h