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Structural basis for the glycosyltransferase activity of the Salmonella effector SseK3

The Salmonella-secreted effector SseK3 translocates into host cells, targeting innate immune responses, including NF-κB activation. SseK3 is a glycosyltransferase that transfers an N-acetylglucosamine (GlcNAc) moiety onto the guanidino group of a target arginine, modulating host cell function. Howev...

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Detalles Bibliográficos
Autores principales: Esposito, Diego, Günster, Regina A., Martino, Luigi, El Omari, Kamel, Wagner, Armin, Thurston, Teresa L. M., Rittinger, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892559/
https://www.ncbi.nlm.nih.gov/pubmed/29449376
http://dx.doi.org/10.1074/jbc.RA118.001796