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Phosphorylation of CDC25C by AMP-activated protein kinase mediates a metabolic checkpoint during cell-cycle G(2)/M-phase transition

From unicellular to multicellular organisms, cell-cycle progression is tightly coupled to biosynthetic and bioenergetic demands. Accumulating evidence has demonstrated the G(1)/S-phase transition as a key checkpoint where cells respond to their metabolic status and commit to replicating the genome....

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Detalles Bibliográficos
Autores principales: Shen, Yuqing, Sherman, John William, Chen, Xuyong, Wang, Ruoning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892595/
https://www.ncbi.nlm.nih.gov/pubmed/29467227
http://dx.doi.org/10.1074/jbc.RA117.001379