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Deficiency in DNA damage response of enterocytes accelerates intestinal stem cell aging in Drosophila

Stem cell dysfunction is closely linked to tissue and organismal aging and age-related diseases, and heavily influenced by the niche cells’ environment. The DNA damage response (DDR) is a key pathway for tissue degeneration and organismal aging; however, the precise protective role of DDR in stem ce...

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Detalles Bibliográficos
Autores principales: Park, Joung-Sun, Jeon, Ho-Jun, Pyo, Jung-Hoon, Kim, Young-Shin, Yoo, Mi-Ae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892683/
https://www.ncbi.nlm.nih.gov/pubmed/29514136
http://dx.doi.org/10.18632/aging.101390