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Deficiency in DNA damage response of enterocytes accelerates intestinal stem cell aging in Drosophila
Stem cell dysfunction is closely linked to tissue and organismal aging and age-related diseases, and heavily influenced by the niche cells’ environment. The DNA damage response (DDR) is a key pathway for tissue degeneration and organismal aging; however, the precise protective role of DDR in stem ce...
Autores principales: | Park, Joung-Sun, Jeon, Ho-Jun, Pyo, Jung-Hoon, Kim, Young-Shin, Yoo, Mi-Ae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892683/ https://www.ncbi.nlm.nih.gov/pubmed/29514136 http://dx.doi.org/10.18632/aging.101390 |
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