Strong impact of natural-selection–free heterogeneity in genetics of age-related phenotypes

A conceptual difficulty in genetics of age-related phenotypes that make individuals vulnerable to disease in post-reproductive life is genetic heterogeneity attributed to an undefined role of evolution in establishing their molecular mechanisms. Here, we performed univariate and pleiotropic genome-w...

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Detalles Bibliográficos
Autores principales: Kulminski, Alexander M., Huang, Jian, Loika, Yury, Arbeev, Konstantin G., Bagley, Olivia, Yashkin, Arseniy, Duan, Matt, Culminskaya, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892700/
https://www.ncbi.nlm.nih.gov/pubmed/29615537
http://dx.doi.org/10.18632/aging.101407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892700/
https://www.ncbi.nlm.nih.gov/pubmed/29615537
http://dx.doi.org/10.18632/aging.101407

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