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Strong impact of natural-selection–free heterogeneity in genetics of age-related phenotypes
A conceptual difficulty in genetics of age-related phenotypes that make individuals vulnerable to disease in post-reproductive life is genetic heterogeneity attributed to an undefined role of evolution in establishing their molecular mechanisms. Here, we performed univariate and pleiotropic genome-w...
Autores principales: | Kulminski, Alexander M., Huang, Jian, Loika, Yury, Arbeev, Konstantin G., Bagley, Olivia, Yashkin, Arseniy, Duan, Matt, Culminskaya, Irina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892700/ https://www.ncbi.nlm.nih.gov/pubmed/29615537 http://dx.doi.org/10.18632/aging.101407 |
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